4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid

4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid is a synthetic small molecule belonging to the phenylpyridine class of organic compounds. It has been studied primarily as an experimental research tool and is not approved for clinical use. The compound acts as a potent inhibitor of serine/threonine-protein kinase Sgk1 (SGK1), with reported IC50 values in the nanomolar range. SGK1 is involved in various cellular processes including ion transport and cell survival pathways. In preclinical studies, inhibition of SGK1 by this compound has shown effects such as modulation of pain behavior and interference with protein-protein interactions relevant to disease models. There are no known brand names or marketed formulations for this substance; it is used mainly in laboratory research settings[2][3][6].

Other names

4-{5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl}benzoic acidBenzoic acid, 4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-